Reaction Details Report a problem with these data
Target
Corticotropin-releasing factor receptor 1
Ligand
BDBM50158953
Substrate
n/a
Meas. Tech.
ChEMBL_304278 (CHEMBL829879)
EC50
65±n/a nM
Citation
 Isfort, RJ; Wang, F; Tscheiner, M; Donnelly, E; Bauer, MB; Lefever, F; Hinkle, RT; Mazur, AW Discovery of corticotropin releasing factor 2 receptor selective sauvagine analogues for treatment of skeletal muscle atrophy. J Med Chem 48:262-5 (2005) [PubMed]  Article 
Target
Name:
Corticotropin-releasing factor receptor 1
Synonyms:
CRF-R | CRF1 | CRFR1_MOUSE | CRH-R 1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing hormone receptor 1 | Crhr | Crhr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47795.13
Organism:
MOUSE
Description:
CRF1 CRHR1 MOUSE::P35347
Residue:
415
Sequence:
MGQRPQLRLVKALLLLGLNPVSTSLQDQQCESLSLASNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHIAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
  
Inhibitor
Name:
BDBM50158953
Synonyms:
CHEMBL438928 | Sauvagine derivative
Type:
Small organic molecule
Emp. Form.:
C208H345N57O62S
Mol. Mass.:
4668.375
SMILES:
n/a
Structure:
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