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Target
Translocator protein
Ligand
BDBM22041
Substrate
n/a
Meas. Tech.
ChEMBL_2191888 (CHEMBL5104248)
Ki
7.9±n/a nM
Citation
Barresi, E; Robello, M; Costa, B; Da Pozzo, E; Baglini, E; Salerno, S; Da Settimo, F; Martini, C; Taliani, S An update into the medicinal chemistry of translocator protein (TSPO) ligands. Eur J Med Chem 209:0 (2021) [PubMed]
More Info.:
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rattus norvegicus (rat)
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE