Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50589230
Substrate
n/a
Meas. Tech.
ChEMBL_2193040 (CHEMBL5105400)
Ki
0.300000±n/a nM
Citation
 Ma, BB; Montgomery, AP; Chen, B; Kassiou, M; Danon, JJ Strategies for targeting the P2Y Bioorg Med Chem Lett 71:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50589230
Synonyms:
CHEMBL5181634
Type:
Small organic molecule
Emp. Form.:
C17H18F4N6OS
Mol. Mass.:
430.423
SMILES:
CCCc1cc2c(nc(OCCF)nc2s1)N1CCn2c(C1)nnc2C(F)(F)F
Structure:
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