Reaction Details Report a problem with these data
Target
Tubulin beta chain [1-43]
Ligand
BDBM50160800
Substrate
n/a
Meas. Tech.
ChEMBL_311916 (CHEMBL834683)
IC50
30000±n/a nM
Citation
 Morita, H; Koyama, K; Sugimoto, Y; Kobayashi, J Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata. Bioorg Med Chem Lett 15:1051-4 (2005) [PubMed]  Article 
Target
Name:
Tubulin beta chain [1-43]
Synonyms:
Beta tubulin | TBB_LEIME
Type:
PROTEIN
Mol. Mass.:
4652.47
Organism:
Leishmania donovani
Description:
ChEMBL_311916
Residue:
43
Sequence:
MREIVSCQAGQCGNQIGSKFWEVIADEHGVDPTGSYQGDSDLQ
  
Inhibitor
Name:
BDBM50160800
Synonyms:
1,3-Bis-(4-hydroxy-benzyl)-4-methoxy-9,10-dihydro-phenanthrene-2,7-diol | CHEMBL181587
Type:
Small organic molecule
Emp. Form.:
C29H26O5
Mol. Mass.:
454.5137
SMILES:
COc1c(Cc2ccc(O)cc2)c(O)c(Cc2ccc(O)cc2)c2CCc3cc(O)ccc3-c12
Structure:
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