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Target
Tubulin beta chain [1-43]
Ligand
BDBM50160803
Substrate
n/a
Meas. Tech.
ChEMBL_311916 (CHEMBL834683)
IC50
30000±n/a nM
Citation
 Morita, H; Koyama, K; Sugimoto, Y; Kobayashi, J Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata. Bioorg Med Chem Lett 15:1051-4 (2005) [PubMed]  Article 
Target
Name:
Tubulin beta chain [1-43]
Synonyms:
Beta tubulin | TBB_LEIME
Type:
PROTEIN
Mol. Mass.:
4652.47
Organism:
Leishmania donovani
Description:
ChEMBL_311916
Residue:
43
Sequence:
MREIVSCQAGQCGNQIGSKFWEVIADEHGVDPTGSYQGDSDLQ
  
Inhibitor
Name:
BDBM50160803
Synonyms:
4,4''-Dimethoxy-9,10,9'',10''-tetrahydro-[1,3'']biphenanthrenyl-2,7,2'',7''-tetraol | CHEMBL185178
Type:
Small organic molecule
Emp. Form.:
C30H26O6
Mol. Mass.:
482.5238
SMILES:
COc1cc(O)c(c2CCc3cc(O)ccc3-c12)-c1c(O)cc2CCc3cc(O)ccc3-c2c1OC |(-6.97,.26,;-5.64,1.03,;-4.31,.27,;-4.31,-1.28,;-2.98,-2.05,;-2.98,-3.58,;-1.65,-1.28,;-1.65,.26,;-.32,1.03,;-.3,2.56,;-1.63,3.33,;-1.6,4.85,;-2.93,5.65,;-2.93,7.18,;-4.29,4.89,;-4.31,3.35,;-2.98,2.57,;-2.98,1.04,;-.32,-2.05,;-.32,-3.59,;-1.65,-4.36,;1.01,-4.36,;2.34,-3.59,;3.67,-4.36,;5.02,-3.59,;5.02,-2.05,;6.38,-1.27,;6.38,.28,;7.73,1.05,;5.02,1.07,;3.69,.3,;3.69,-1.26,;2.34,-2.05,;1.01,-1.27,;1.01,.26,;2.34,1.03,)|
Structure:
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