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Target
Thromboxane A2 receptor
Ligand
BDBM50160915
Substrate
n/a
Meas. Tech.
ChEMBL_302705 (CHEMBL839577)
Ki
>21000±n/a nM
Citation
 Ducharme, Y; Blouin, M; Carrière, MC; Chateauneuf, A; Côté, B; Denis, D; Frenette, R; Greig, G; Kargman, S; Lamontagne, S; Martins, E; Nantel, F; O'Neill, G; Sawyer, N; Metters, KM; Friesen, RW 2,3-Diarylthiophenes as selective EP1 receptor antagonists. Bioorg Med Chem Lett 15:1155-60 (2005) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50160915
Synonyms:
CHEMBL180046 | N-{3-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-phenyl}-2-phenyl-acetamide
Type:
Small organic molecule
Emp. Form.:
C31H24ClNO2S
Mol. Mass.:
510.046
SMILES:
Clc1ccc(OCc2ccccc2)c(c1)-c1ccsc1-c1cccc(NC(=O)Cc2ccccc2)c1
Structure:
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