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Target
D(3) dopamine receptor
Ligand
BDBM50030196
Substrate
n/a
Meas. Tech.
ChEMBL_2194223 (CHEMBL5106583)
Ki
617±n/a nM
Citation
 Pavleti?, P; Semeano, A; Yano, H; Bonifazi, A; Giorgioni, G; Piergentili, A; Quaglia, W; Sabbieti, MG; Agas, D; Santoni, G; Pallini, R; Ricci-Vitiani, L; Sabato, E; Vistoli, G; Del Bello, F Highly Potent and Selective Dopamine D J Med Chem 65:12124-12139 (2022) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50030196
Synonyms:
CHEMBL3354065
Type:
Small organic molecule
Emp. Form.:
C21H32N2O
Mol. Mass.:
328.4916
SMILES:
CCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1
Structure:
Search PDB for entries with ligand similarity: