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Target
Sortase family protein
Ligand
BDBM50590366
Substrate
n/a
Meas. Tech.
ChEMBL_2196378 (CHEMBL5108894)
IC50
500±n/a nM
Citation
 Guan, XN; Zhang, T; Yang, T; Dong, Z; Yang, S; Lan, L; Gan, J; Yang, CG Covalent sortase A inhibitor ML346 prevents  RSC Med Chem 13:138-149 (2022) [PubMed] 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50590366
Synonyms:
CHEMBL5174805
Type:
Small organic molecule
Emp. Form.:
C14H12N2O4
Mol. Mass.:
272.2561
SMILES:
[#6]-[#8]-c1ccc(\[#6]=[#6]\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)cc1
Structure:
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