Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 3
Ligand
BDBM50162394
Substrate
n/a
Meas. Tech.
ChEMBL_303563 (CHEMBL828963)
Ki
429.0±n/a nM
Citation
 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Novel ligands for the chemokine receptor-3 (CCR3): a receptor-modeling study based on 5D-QSAR. J Med Chem 48:1515-27 (2005) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 3
Synonyms:
C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor
Type:
Enzyme
Mol. Mass.:
41053.88
Organism:
Homo sapiens (Human)
Description:
P51677
Residue:
355
Sequence:
MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
  
Inhibitor
Name:
BDBM50162394
Synonyms:
1-(4-Chloro-phenyl)-3-[2-(4-cyclohexyl-piperazin-1-yl)-4-methyl-pentyl]-urea | CHEMBL193916
Type:
Small organic molecule
Emp. Form.:
C23H37ClN4O
Mol. Mass.:
421.019
SMILES:
CC(C)CC(CNC(=O)Nc1ccc(Cl)cc1)N1CCN(CC1)C1CCCCC1
Structure:
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