Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50590649
Substrate
n/a
Meas. Tech.
ChEMBL_2197403 (CHEMBL5109919)
Ki
0.010000±n/a nM
Citation
 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors. J Med Chem 65:10755-10808 (2022) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT1B | 5HT1B_CAVPO | HTR1B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43125.84
Organism:
GUINEA PIG
Description:
5-HT1B HTR1B GUINEA PIG::O08892
Residue:
389
Sequence:
MGNPEASCTPPAVLGSQTGLPHANVSAPPNNCSAPSHIYQDSIALPWKVLLVVLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAFTDLLVSILVMPISTMYTVTGRWTLGQALCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVGYSAKRTPRRAAGMIALVWVFSICISLPPFFWRQAKAEEEVLDCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPCDSGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGVILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTT
  
Inhibitor
Name:
BDBM50590649
Synonyms:
CHEMBL5209320
Type:
Small organic molecule
Emp. Form.:
C26H30N4O4
Mol. Mass.:
461.5415
SMILES:
Cc1ccc(N2CCN([11CH3])CC2)c2oc(cc(=O)c12)C(=O)Nc1ccc(cc1)N1CCOCC1
Structure:
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