Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50162694
Substrate
n/a
Meas. Tech.
ChEMBL_305485 (CHEMBL830276)
IC50
2.8±n/a nM
Citation
 Guba, W; Neidhart, W; Nettekoven, M Novel and potent NPY5 receptor antagonists derived from virtual screening and iterative parallel chemistry design. Bioorg Med Chem Lett 15:1599-603 (2005) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r
Type:
Enzyme
Mol. Mass.:
52807.91
Organism:
Mus musculus (Mouse)
Description:
O70342
Residue:
466
Sequence:
MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
  
Inhibitor
Name:
BDBM50162694
Synonyms:
3-[5-(2-Ethyl-benzoyl)-thiazol-2-ylamino]-benzonitrile | CHEMBL180692
Type:
Small organic molecule
Emp. Form.:
C19H15N3OS
Mol. Mass.:
333.407
SMILES:
CCc1ccccc1C(=O)c1cnc(Nc2cccc(c2)C#N)s1
Structure:
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