Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50162334
Substrate
n/a
Meas. Tech.
ChEMBL_2197637 (CHEMBL5110153)
Ki
21000±n/a nM
Citation
 Das, A; Dasgupta, S; Pathak, T Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors. Bioorg Med Chem 71:0 (2022) [PubMed] 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50162334
Synonyms:
5-[3-carboxy-4-(3-nitrophenylcarboxamido)benzyl]-2-(3-nitrophenylcarboxamido)benzoic acid | CHEMBL365182
Type:
Small organic molecule
Emp. Form.:
C29H20N4O10
Mol. Mass.:
584.4899
SMILES:
OC(=O)c1cc(Cc2ccc(NC(=O)c3cccc(c3)[N+]([O-])=O)c(c2)C(O)=O)ccc1NC(=O)c1cccc(c1)[N+]([O-])=O
Structure:
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