Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50590730
Substrate
n/a
Meas. Tech.
ChEMBL_2197641 (CHEMBL5110157)
Ki
32000±n/a nM
Citation
 Das, A; Dasgupta, S; Pathak, T Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors. Bioorg Med Chem 71:0 (2022) [PubMed] 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50590730
Synonyms:
CHEMBL5179731
Type:
Small organic molecule
Emp. Form.:
C12H12N6O6S2
Mol. Mass.:
400.39
SMILES:
OS(=O)(=O)Cc1cn(nn1)-c1cccc(c1)-n1cc(CS(O)(=O)=O)nn1
Structure:
Search PDB for entries with ligand similarity: