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Target
Phospholipase A2, major isoenzyme
Ligand
BDBM50591712
Substrate
n/a
Meas. Tech.
ChEMBL_2201654 (CHEMBL5114362)
IC50
12400±n/a nM
Citation
 Jiang, X; Wu, K; Bai, R; Zhang, P; Zhang, Y Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities. Eur J Med Chem 229:0 (2022) [PubMed] 
Target
Name:
Phospholipase A2, major isoenzyme
Synonyms:
Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2
Type:
Hydrolase; monomer or homodimer
Mol. Mass.:
16279.83
Organism:
Sus scrofa (pig)
Description:
Purchased from Sigma.
Residue:
146
Sequence:
MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC
  
Inhibitor
Name:
BDBM50591712
Synonyms:
CHEMBL5194852
Type:
Small organic molecule
Emp. Form.:
C16H14N4O2
Mol. Mass.:
294.308
SMILES:
COc1cccc(\C=N\Nc2nc3ccccc3[nH]c2=O)c1
Structure:
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