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Target
Phospholipase A2, major isoenzyme
Ligand
BDBM50591715
Substrate
n/a
Meas. Tech.
ChEMBL_2201654 (CHEMBL5114362)
IC50
14490±n/a nM
Citation
 Jiang, X; Wu, K; Bai, R; Zhang, P; Zhang, Y Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities. Eur J Med Chem 229:0 (2022) [PubMed] 
Target
Name:
Phospholipase A2, major isoenzyme
Synonyms:
Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2
Type:
Hydrolase; monomer or homodimer
Mol. Mass.:
16279.83
Organism:
Sus scrofa (pig)
Description:
Purchased from Sigma.
Residue:
146
Sequence:
MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC
  
Inhibitor
Name:
BDBM50591715
Synonyms:
CHEMBL5179709
Type:
Small organic molecule
Emp. Form.:
C17H10Cl2N2O
Mol. Mass.:
329.18
SMILES:
Clc1ccc(cc1Cl)-c1ccc2n1c1ccccc1[nH]c2=O
Structure:
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