Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50164427
Substrate
n/a
Meas. Tech.
ChEMBL_303231 (CHEMBL827196)
Ki
40±n/a nM
Citation
 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hübner, H; Gmeiner, P CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists. J Med Chem 48:2493-508 (2005) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50164427
Synonyms:
(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbonitrile | CHEMBL372020
Type:
Small organic molecule
Emp. Form.:
C15H23N3
Mol. Mass.:
245.3632
SMILES:
CCCN(CCC)[C@H]1CCn2c(C1)ccc2C#N
Structure:
Search PDB for entries with ligand similarity: