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Target
Adenosine receptor A2a
Ligand
BDBM50165065
Substrate
n/a
Meas. Tech.
ChEMBL_303597 (CHEMBL829686)
Ki
7.1±n/a nM
Citation
 Kiselgof, E; Tulshian, DB; Arik, L; Zhang, H; Fawzi, A 6-(2-Furanyl)-9H-purin-2-amine derivatives as A2A adenosine antagonists. Bioorg Med Chem Lett 15:2119-22 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50165065
Synonyms:
9-(2,6-Dichloro-benzyl)-6-furan-2-yl-9H-purin-2-ylamine | CHEMBL193414
Type:
Small organic molecule
Emp. Form.:
C16H11Cl2N5O
Mol. Mass.:
360.197
SMILES:
Nc1nc(-c2ccco2)c2ncn(Cc3c(Cl)cccc3Cl)c2n1
Structure:
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