Target
Adenosine receptor A2a
Ligand
BDBM50165066
Substrate
n/a
Meas. Tech.
ChEMBL_303597 (CHEMBL829686)
Ki
34.9±n/a nM
Citation
 Kiselgof, ETulshian, DBArik, LZhang, HFawzi, A 6-(2-Furanyl)-9H-purin-2-amine derivatives as A2A adenosine antagonists. Bioorg Med Chem Lett 15:2119-22 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50165066
Synonyms:
9-Benzyl-6-furan-2-yl-9H-purin-2-ylamine | 9-benzyl-6-(furan-2-yl)-9H-purin-2-amine | CHEMBL196436
Type:
Small organic molecule
Emp. Form.:
C16H13N5O
Mol. Mass.:
291.3073
SMILES:
Nc1nc(-c2ccco2)c2ncn(Cc3ccccc3)c2n1
Structure:
Search PDB for entries with ligand similarity: