Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM50272460
Substrate
n/a
Meas. Tech.
ChEMBL_2204527 (CHEMBL5117235)
Kd
>1000000±n/a nM
Citation
 Fu, J; He, Z; Fu, H; Xia, Y; N'Go, I; Lou, H; Wu, J; Pan, W; Vincent, SP Synthesis and evaluation of inhibitors of Mycobacterium tuberculosis UGM using bioisosteric replacement. Bioorg Med Chem 69:0 (2022) [PubMed] 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM50272460
Synonyms:
CHEMBL3276007
Type:
Small organic molecule
Emp. Form.:
C18H17NO3
Mol. Mass.:
295.3325
SMILES:
OC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: