Reaction Details Report a problem with these data
Target
NAD kinase
Ligand
BDBM50373220
Substrate
n/a
Meas. Tech.
ChEMBL_2207960 (CHEMBL5120668)
IC50
>100000±n/a nM
Citation
 Liu, T; Shi, W; Ding, Y; Wu, Q; Zhang, B; Zhang, N; Wang, M; Du, D; Zhang, H; Han, B; Guo, D; Zheng, J; Li, Q; Luo, C (-)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase. ACS Med Chem Lett 13:1699-1706 (2022) [PubMed] 
Target
Name:
NAD kinase
Synonyms:
NADK | NADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
49227.18
Organism:
Homo sapiens (Human)
Description:
ChEMBL_578494
Residue:
446
Sequence:
MEMEQEKMTMNKELSPDAAAYCCSACHGDETWSYNHPIRGRAKSRSLSASPALGSTKEFRRTRSLHGPCPVTTFGPKACVLQNPQTIMHIQDPASQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFEEEEEEEEEG
  
Inhibitor
Name:
BDBM50373220
Synonyms:
(-)-GALLOCATECHIN
Type:
Small organic molecule
Emp. Form.:
C15H14O7
Mol. Mass.:
306.2675
SMILES:
O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c1cc(O)c(O)c(O)c1
Structure:
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