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Target
Neuropeptide Y receptor type 5
Ligand
BDBM50168692
Substrate
n/a
Meas. Tech.
ChEMBL_305083 (CHEMBL832713)
IC50
17±n/a nM
Citation
 Nettekoven, M; Guba, W; Neidhart, W; Mattei, P; Pflieger, P; Roche, O; Taylor, S Isomeric thiazole derivatives as ligands for the neuropeptide Y5 receptor. Bioorg Med Chem Lett 15:3446-9 (2005) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r
Type:
Enzyme
Mol. Mass.:
52807.91
Organism:
Mus musculus (Mouse)
Description:
O70342
Residue:
466
Sequence:
MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
  
Inhibitor
Name:
BDBM50168692
Synonyms:
2,5-Dimethoxy-N-{3-[4-(2-methyl-benzoyl)-thiazol-2-ylamino]-propyl}-benzenesulfonamide | CHEMBL365021
Type:
Small organic molecule
Emp. Form.:
C22H25N3O5S2
Mol. Mass.:
475.581
SMILES:
COc1ccc(OC)c(c1)S(=O)(=O)NCCCNc1nc(cs1)C(=O)c1ccccc1C
Structure:
Search PDB for entries with ligand similarity: