Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM50262559
Substrate
n/a
Meas. Tech.
ChEMBL_2214324 (CHEMBL5127456)
Kd
>2000000±n/a nM
Citation
 Alizadeh, SR; Ebrahimzadeh, MA Quercetin derivatives: Drug design, development, and biological activities, a review. Eur J Med Chem 229:0 (2022) [PubMed] 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM50262559
Synonyms:
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-(piperidin-1-ylmethyl)-4H-chromen-4-one | CHEMBL478849
Type:
Small organic molecule
Emp. Form.:
C21H21NO7
Mol. Mass.:
399.3939
SMILES:
Oc1ccc(cc1O)-c1oc2c(CN3CCCCC3)c(O)cc(O)c2c(=O)c1O
Structure:
Search PDB for entries with ligand similarity: