Reaction Details Report a problem with these data
Target
Casein kinase II subunit alpha 3
Ligand
BDBM50595189
Substrate
n/a
Meas. Tech.
ChEMBL_2215719 (CHEMBL5128851)
IC50
180±n/a nM
Citation
 Wang, Q; Hu, X; Shi, W; Long, H; Wang, H Design, synthesis and biological evaluation of chromone derivatives as novel protein kinase CK2 inhibitors. Bioorg Med Chem Lett 69:0 (2022) [PubMed] 
Target
Name:
Casein kinase II subunit alpha 3
Synonyms:
2.7.11.1 | CK II alpha 3 | CSK23_HUMAN | CSNK2A1P | CSNK2A3 | Casein kinase II alpha 1 polypeptide pseudogene | Casein kinase II subunit alpha 3
Type:
PROTEIN
Mol. Mass.:
45229.76
Organism:
Homo sapiens
Description:
ChEMBL_116899
Residue:
391
Sequence:
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYDQLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANVMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAATGAQQ
  
Inhibitor
Name:
BDBM50595189
Synonyms:
CHEMBL5190817
Type:
Small organic molecule
Emp. Form.:
C20H11F3N2O4S
Mol. Mass.:
432.373
SMILES:
FC(F)(F)Oc1ccc(cc1)-c1csc(NC(=O)c2cc(=O)c3ccccc3o2)n1
Structure:
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