Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50169751
Substrate
n/a
Meas. Tech.
ChEMBL_302892 (CHEMBL830208)
Ki
420±n/a nM
Citation
 Yates, AS; Doughty, SW; Kendall, DA; Kellam, B Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB2 receptor. Bioorg Med Chem Lett 15:3758-62 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50169751
Synonyms:
CHEMBL555145 | [4-(2-Methyl-1-propyl-1H-indole-3-carbonyl)-naphthalen-2-ylcarbamoyl]-methyl-ammonium; chloride
Type:
Small organic molecule
Emp. Form.:
C25H26N3O2
Mol. Mass.:
400.4923
SMILES:
CCCn1c(C)c(C(=O)c2cc(NC(=O)C[NH3+])cc3ccccc23)c2ccccc12
Structure:
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