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Target
Mitogen-activated protein kinase 2
Ligand
BDBM50045333
Substrate
n/a
Meas. Tech.
ChEMBL_2218396 (CHEMBL5131730)
IC50
105±n/a nM
Citation
 Raghuvanshi, R; Bharate, SB Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections. J Med Chem 65:893-921 (2022) [PubMed] 
Target
Name:
Mitogen-activated protein kinase 2
Synonyms:
2.7.11.24 | MAPK | MAPK2_PNECA | MKP2 | PCM | Synonyms=MAPK
Type:
PROTEIN
Mol. Mass.:
40571.72
Organism:
Pneumocystis carinii
Description:
ChEMBL_120758
Residue:
351
Sequence:
MTASSRNVRFNVSDDYEILDVIGEGAYGIVCSAIHKPSGQKVAIKKISPFDHSMFCLRTLREMKLLRYFNHENIISILDIQQPQDFESFSEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQILRALKAMHSADILHRDLKPSNLLLNANCDLKVCDFGLARSAVSTEDSSSFMTEYVATRWYRAPEIMLTFKEYTKAIDIWSVGCILAEMLSGRPLFPGKDYHHQLMLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKRVSFASIFPRANPLALDLLEKLLAFNPAKRVTAEEALQHNYLEPYHDPDDEPTAPPISPSFFDFDRIKDSLTKNDLKILIYKEIMSMNN
  
Inhibitor
Name:
BDBM50045333
Synonyms:
CHEBI:90705 | SB-203580
Type:
Small organic molecule
Emp. Form.:
C21H16FN3OS
Mol. Mass.:
377.435
SMILES:
C[S+]([O-])c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1
Structure:
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