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Target
Protein ENL
Ligand
BDBM50596391
Substrate
n/a
Meas. Tech.
ChEMBL_2220373 (CHEMBL5133707)
Kd
5000±n/a nM
Citation
 Pu, DB; Guo, SQ; Ni, DX; Lin, J; Gao, JB; Li, XN; Zhang, RH; Li, XL; Luo, C; Chen, SJ; Xiao, WL Spiroarborin, an  J Nat Prod 85:317-326 (2022) [PubMed] 
Target
Name:
Protein ENL
Synonyms:
ENL | ENL_HUMAN | LTG19 | MLLT1 | Protein ENL | YEATS domain-containing protein 1 | YEATS1
Type:
PROTEIN
Mol. Mass.:
62068.50
Organism:
Homo sapiens
Description:
ChEMBL_118046
Residue:
559
Sequence:
MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT
  
Inhibitor
Name:
BDBM50596391
Synonyms:
CHEMBL5171384
Type:
Small organic molecule
Emp. Form.:
C40H56O10
Mol. Mass.:
696.8666
SMILES:
[H][C@]12CCC3=C(CCC4(O3)C(=O)CC[C@]3([H])[C@@](C)(C[C@H](O)C5=CC(=O)OC5O)[C@H](C)CC[C@@]43C)[C@]1(C)CC[C@@H](C)[C@]2(C)C[C@H](O)C1=CC(=O)OC1O |r,t:4,22,51|
Structure:
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