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Target
D(3) dopamine receptor
Ligand
BDBM50172863
Substrate
n/a
Meas. Tech.
ChEMBL_320854 (CHEMBL884779)
Ki
1.1±n/a nM
Citation
 Hocke, C; Prante, O; Löber, S; Hübner, H; Gmeiner, P; Kuwert, T Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. Bioorg Med Chem Lett 15:4819-23 (2005) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50172863
Synonyms:
CHEMBL197162 | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-6-fluoronicotinamide | N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-6-fluoro-nicotinamide
Type:
Small organic molecule
Emp. Form.:
C20H23Cl2FN4O
Mol. Mass.:
425.327
SMILES:
Fc1ccc(cn1)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl
Structure:
Search PDB for entries with ligand similarity: