Reaction Details Report a problem with these data
Target
Gastric inhibitory polypeptide receptor
Ligand
BDBM50597205
Substrate
n/a
Meas. Tech.
ChEMBL_2223097 (CHEMBL5136431)
EC50
38±n/a nM
Citation
 Sabnis, RW Novel 6-Methoxy-3,4-dihydro-1 ACS Med Chem Lett 13:891-892 (2022) [PubMed] 
Target
Name:
Gastric inhibitory polypeptide receptor
Synonyms:
GIPR | GIPR_HUMAN | Gastric Inhibitory Polypeptide Receptor (GIPR) | Gastric inhibitory polypeptide receptor
Type:
PROTEIN
Mol. Mass.:
53173.82
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1518286
Residue:
466
Sequence:
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
  
Inhibitor
Name:
BDBM50597205
Synonyms:
CHEMBL5184469
Type:
Small organic molecule
Emp. Form.:
C29H34FNO2
Mol. Mass.:
447.5842
SMILES:
COc1ccc2[C@@H](C)N(CCc2c1-c1cc(C)c(O)c(F)c1)C(C)c1ccc(cc1)C(C)C |r|
Structure:
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