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Target
Somatostatin receptor type 4
Ligand
BDBM523763
Substrate
n/a
Meas. Tech.
ChEMBL_2223692 (CHEMBL5137205)
Ki
3.1±n/a nM
Citation
 Neumann, WL; Sandoval, KE; Mobayen, S; Minaeian, M; Kukielski, SG; Srabony, KN; Frare, R; Slater, O; Farr, SA; Niehoff, ML; Hospital, A; Kontoyianni, M; Crider, AM; Witt, KA Synthesis and structure-activity relationships of 3,4,5-trisubstituted-1,2,4-triazoles: high affinity and selective somatostatin receptor-4 agonists for Alzheimer's disease treatment. RSC Med Chem 12:1352-1365 (2021) [PubMed] 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM523763
Synonyms:
US11136312, Compound SK-I-53
Type:
Small organic molecule
Emp. Form.:
C25H26N6O
Mol. Mass.:
426.5135
SMILES:
COc1ccc2[nH]cc(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c2c1
Structure:
Search PDB for entries with ligand similarity: