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Target
Somatostatin receptor type 1
Ligand
BDBM523734
Substrate
n/a
Meas. Tech.
ChEMBL_2223693 (CHEMBL5137206)
Ki
6929±n/a nM
Citation
 Neumann, WL; Sandoval, KE; Mobayen, S; Minaeian, M; Kukielski, SG; Srabony, KN; Frare, R; Slater, O; Farr, SA; Niehoff, ML; Hospital, A; Kontoyianni, M; Crider, AM; Witt, KA Synthesis and structure-activity relationships of 3,4,5-trisubstituted-1,2,4-triazoles: high affinity and selective somatostatin receptor-4 agonists for Alzheimer's disease treatment. RSC Med Chem 12:1352-1365 (2021) [PubMed] 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM523734
Synonyms:
US11136312, Compound BN-VI-56
Type:
Small organic molecule
Emp. Form.:
C25H25ClN6
Mol. Mass.:
444.959
SMILES:
Clc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1
Structure:
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