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Target
Parkinson disease protein 7
Ligand
BDBM50597603
Substrate
n/a
Meas. Tech.
ChEMBL_2223715 (CHEMBL5137228)
IC50
118±n/a nM
Citation
Maksimovic, I; Finkin-Groner, E; Fukase, Y; Zheng, Q; Sun, S; Michino, M; Huggins, DJ; Myers, RW; David, Y Deglycase-activity oriented screening to identify DJ-1 inhibitors. RSC Med Chem 12:1232-1238 (2021) [PubMed]
More Info.:
Target
Name:
Parkinson disease protein 7
Synonyms:
3.1.2.- | 3.5.1.- | 3.5.1.124 | DJ-1 | Maillard deglycase | Oncogene DJ1 | PARK7 | PARK7_HUMAN | Parkinsonism-associated deglycase | Protein DJ-1 | Protein/nucleic acid deglycase DJ-1
Type:
PROTEIN
Mol. Mass.:
19891.33
Organism:
Homo sapiens
Description:
ChEMBL_120727
Residue:
189
Sequence:
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD