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Target
P2X purinoceptor 5
Ligand
BDBM50598317
Substrate
n/a
Meas. Tech.
ChEMBL_2226721 (CHEMBL5140234)
IC50
1651±n/a nM
Citation
 Mahmood, A; Villinger, A; Iqbal, J Therapeutic potentials and structure-activity relationship of 1,3-benzodioxole N-carbamothioyl carboxamide derivatives as selective and potent antagonists of P2X4 and P2X7 receptors. Eur J Med Chem 238:0 (2022) [PubMed] 
Target
Name:
P2X purinoceptor 5
Synonyms:
ATP receptor | P2RX5 | P2RX5_HUMAN | P2X5 | Purinergic receptor
Type:
PROTEIN
Mol. Mass.:
47208.74
Organism:
Homo sapiens (Human)
Description:
ChEMBL_612725
Residue:
422
Sequence:
MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST
  
Inhibitor
Name:
BDBM50598317
Synonyms:
CHEMBL5208562
Type:
Small organic molecule
Emp. Form.:
C15H11N3O5S
Mol. Mass.:
345.33
SMILES:
[O-][N+](=O)c1ccc(NC(=S)NC(=O)c2ccc3OCOc3c2)cc1
Structure:
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