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Target
G-protein coupled receptor 84
Ligand
BDBM50599076
Substrate
n/a
Meas. Tech.
ChEMBL_2228897 (CHEMBL5142410)
IC50
17±n/a nM
Citation
 Mahindra, A; Jenkins, L; Marsango, S; Huggett, M; Huggett, M; Robinson, L; Gillespie, J; Rajamanickam, M; Morrison, A; McElroy, S; Tikhonova, IG; Milligan, G; Jamieson, AG Investigating the Structure-Activity Relationship of 1,2,4-Triazine G-Protein-Coupled Receptor 84 (GPR84) Antagonists. J Med Chem 65:11270-11290 (2022) [PubMed] 
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50599076
Synonyms:
CHEMBL5186601
Type:
Small organic molecule
Emp. Form.:
C23H17N5
Mol. Mass.:
363.4146
SMILES:
C(c1c[nH]c2ccncc12)c1nnc(-c2ccccc2)c(n1)-c1ccccc1
Structure:
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