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Target
Mu-type opioid receptor
Ligand
BDBM50599576
Substrate
n/a
Meas. Tech.
ChEMBL_2231098 (CHEMBL5144870)
Ki
0.126000±n/a nM
Citation
 Uenohara, Y; Tsumura, S; Hirayama, S; Higashi, E; Watanabe, Y; Gouda, H; Nagase, H; Fujii, H Morphinan derivatives with an oxabicyclo[3.2.1]octane structure as dual agonists toward ? and ? opioid receptors. Bioorg Med Chem 53:0 (2022) [PubMed] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50599576
Synonyms:
CHEMBL5200218
Type:
Small organic molecule
Emp. Form.:
C30H36N2O3
Mol. Mass.:
472.6184
SMILES:
[H][C@@]12CC[C@@]3(O1)[C@@]1([H])Cc4ccc(O)cc4[C@@]3(CCN1CC1CC1)C[C@H]2NC(=O)CCc1ccccc1 |r,TLB:20:19:4:8.9.15|
Structure:
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