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Target
Mu-type opioid receptor
Ligand
BDBM50177899
Substrate
n/a
Meas. Tech.
ChEMBL_325740 (CHEMBL864530)
Ki
0.74±n/a nM
Citation
 Henriksen, G; Platzer, S; Marton, J; Hauser, A; Berthele, A; Schwaiger, M; Marinelli, L; Lavecchia, A; Novellino, E; Wester, HJ Syntheses, biological evaluation, and molecular modeling of 18F-labeled 4-anilidopiperidines as mu-opioid receptor imaging agents. J Med Chem 48:7720-32 (2005) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50177899
Synonyms:
CHEMBL371710 | methyl 4-[(N-1-oxopropyl)-N-phenylamino]-1-(5-[18F]-fluoropentyl)-4-piperidinecarboxylate
Type:
Small organic molecule
Emp. Form.:
C21H31FN2O3
Mol. Mass.:
378.4808
SMILES:
CCC(=O)N(c1ccccc1)C1(CCN(CCCCCF)CC1)C(=O)OC
Structure:
Search PDB for entries with ligand similarity: