Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 1
Ligand
BDBM50098647
Substrate
n/a
Meas. Tech.
ChEMBL_2236358 (CHEMBL5150254)
IC50
800±n/a nM
Citation
 Maia, M; Resende, DISP; Durães, F; Pinto, MMM; Sousa, E Xanthenes in Medicinal Chemistry - Synthetic strategies and biological activities. Eur J Med Chem 210:0 (2021) [PubMed] 
Target
Name:
C-C chemokine receptor type 1
Synonyms:
C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1
Type:
Enzyme
Mol. Mass.:
41180.69
Organism:
Homo sapiens (Human)
Description:
P32246
Residue:
355
Sequence:
METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
  
Inhibitor
Name:
BDBM50098647
Synonyms:
9H-Xanthene-9-carboxylic acid (1-cyclodecylmethyl-piperidin-4-yl)-amide | CHEMBL285703
Type:
Small organic molecule
Emp. Form.:
C30H40N2O2
Mol. Mass.:
460.6508
SMILES:
O=C(NC1CCN(CC2CCCCCCCCC2)CC1)C1c2ccccc2Oc2ccccc12
Structure:
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