Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50601684
Substrate
n/a
Meas. Tech.
ChEMBL_2237866 (CHEMBL5151762)
Kd
12400±n/a nM
Citation
 Chan, CB; Poulie, CBM; Wismann, SS; Soelberg, J; Kristensen, JL The Alkaloids from  J Nat Prod 84:2398-2407 (2021) [PubMed] 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50601684
Synonyms:
CHEMBL5169925
Type:
Small organic molecule
Emp. Form.:
C9H13NO
Mol. Mass.:
151.2056
SMILES:
CNCCc1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: