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Target
Abscisic acid 8'-hydroxylase 3
Ligand
BDBM50184728
Substrate
n/a
Meas. Tech.
ChEMBL_358214 (CHEMBL865122)
Ki
140±n/a nM
Citation
 Araki, Y; Miyawaki, A; Miyashita, T; Mizutani, M; Hirai, N; Todoroki, Y A new non-azole inhibitor of ABA 8'-hydroxylase: effect of the hydroxyl group substituted for geminal methyl groups in the six-membered ring. Bioorg Med Chem Lett 16:3302-5 (2006) [PubMed]  Article 
Target
Name:
Abscisic acid 8'-hydroxylase 3
Synonyms:
ABAH3_ARATH | CYP707A3 | Cytochrome P450 monooxygenase
Type:
PROTEIN
Mol. Mass.:
52380.10
Organism:
Arabidopsis thaliana
Description:
ChEMBL_358214
Residue:
463
Sequence:
MDFSGLFLTLSAAALFLCLLRFIAGVRRSSSTKLPLPPGTMGYPYVGETFQLYSQDPNVFFAAKQRRYGSVFKTHVLGCPCVMISSPEAAKFVLVTKSHLFKPTFPASKERMLGKQAIFFHQGDYHSKLRKLVLRAFMPDAIRNMVPHIESIAQESLNSWDGTQLNTYQEMKTYTFNVALISILGKDEVYYREDLKRCYYILEKGYNSMPINLPGTLFHKAMKARKELAQILANILSKRRQNPSSHTDLLGSFMEDKAGLTDEQIADNIIGVIFAARDTTASVLTWILKYLADNPTVLEAVTEEQMAIRKDKKEGESLTWEDTKKMPLTYRVIQETLRAATILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHNADIFSDPGKFDPSRFEVAPKPNTFMPFGSGIHSCPGNELAKLEISVLIHHLTTKYRWSIVGPSDGIQYGPFALPQNGLPIALERKP
  
Inhibitor
Name:
BDBM50184728
Synonyms:
5-((1S,2S,6S)-1,2-dihydroxy-6-methylcyclohexyl)penta-2,4-dienoic acid | CHEMBL210878
Type:
Small organic molecule
Emp. Form.:
C12H18O4
Mol. Mass.:
226.2689
SMILES:
C[C@H]1CCC[C@H](O)[C@@]1(O)\C=C\C=C/C(O)=O
Structure:
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