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Target
Serine racemase
Ligand
BDBM50185232
Substrate
n/a
Meas. Tech.
ChEMBL_343501 (CHEMBL860701)
Ki
320000±n/a nM
Citation
 Dixon, SM; Li, P; Liu, R; Wolosker, H; Lam, KS; Kurth, MJ; Toney, MD Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries. J Med Chem 49:2388-97 (2006) [PubMed]  Article 
Target
Name:
Serine racemase
Synonyms:
SRR | SRR_HUMAN
Type:
PROTEIN
Mol. Mass.:
36565.80
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1516972
Residue:
340
Sequence:
MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV
  
Inhibitor
Name:
BDBM50185232
Synonyms:
(S)-2-((S)-3-(1H-imidazol-4-yl)-2-(3-phenylpropanamido)propanamido)-4-phenylbutanamide | CHEMBL378874
Type:
Small organic molecule
Emp. Form.:
C25H29N5O3
Mol. Mass.:
447.5295
SMILES:
NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCc1ccccc1
Structure:
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