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Target
Solute carrier family 15 member 2
Ligand
BDBM50169160
Substrate
n/a
Meas. Tech.
ChEMBL_370529 (CHEMBL871420)
Ki
4000±n/a nM
Citation
 Biegel, A; Gebauer, S; Brandsch, M; Neubert, K; Thondorf, I Structural requirements for the substrates of the H+/peptide cotransporter PEPT2 determined by three-dimensional quantitative structure-activity relationship analysis. J Med Chem 49:4286-96 (2006) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 2
Synonyms:
Oligopeptide transporter, kidney isoform | Pept2 | S15A2_RAT | Slc15a2
Type:
PROTEIN
Mol. Mass.:
81331.63
Organism:
Rattus norvegicus
Description:
ChEMBL_838253
Residue:
729
Sequence:
MNPFQKNESKETLFSPVSTEEMLPRPPSPPKKSPPKIFGSSYPVSIAFIVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEEEHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVKCFGQDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPPEGNIVAQVIKCIWFALCNRFRNRSGDLPKRQHWLDWAAEKYPKHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLGFFVLQPDQMQVLNPFLVLIFIPLFDLVIYRLISKCRINFSSLRKMAVGMILACLAFAVAALVETKINGMIHPQPASQEIFLQVLNLADGDVKVTVLGSRNNSLLVESVSSFQNTTHYSKLHLEAKSQDLHFHLKYNSLSVHNDHSVEEKNCYQLLIHQDGESISSMLVKDTGIKPANGMAAIRFINTLHKDLNISLDTDAPLSVGKDYGVSAYRTVLRGKYPAVHCETEDKVFSLDLGQLDFGTTYLFVITNITSQGLQAWKAEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLVVAQFSGLAQWAEFVLFSCLLLVVCLIFSVMAYYYVPLKSEDTREATDKQIPAVQGNMINLETKNTRL
  
Inhibitor
Name:
BDBM50169160
Synonyms:
(S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)propanoic acid | (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-propionic acid | CHEMBL188866 | Trp-Ala
Type:
Small organic molecule
Emp. Form.:
C14H17N3O3
Mol. Mass.:
275.3031
SMILES:
C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O
Structure:
Search PDB for entries with ligand similarity: