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Target
Somatostatin receptor type 3
Ligand
BDBM50191269
Substrate
n/a
Meas. Tech.
ChEMBL_366814 (CHEMBL865391)
IC50
942±n/a nM
Citation
 Grace, CR; Erchegyi, J; Koerber, SC; Reubi, JC; Rivier, J; Riek, R Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. J Med Chem 49:4487-96 (2006) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50191269
Synonyms:
CHEMBL412029 | H2N-CO-Phe-c[Cys-Aph(CONH2) -DTrp-Lys-Thr-Cys] -Thr-NH2
Type:
Small organic molecule
Emp. Form.:
C51H68N14O12S2
Mol. Mass.:
1133.302
SMILES:
C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(N)=O)C(=O)N[C@@H](Cc2ccc(NC(N)=O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Structure:
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