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Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50191985
Substrate
n/a
Meas. Tech.
ChEMBL_392530 (CHEMBL864291)
Ki
520±n/a nM
Citation
 Sun, Q; Law, A; Crowder, MW; Geysen, HM Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis. Bioorg Med Chem Lett 16:5169-75 (2006) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50191985
Synonyms:
(2R)-2-(4-mercapto-2-(3-(trimethylsilyl)propanamido)butanamido)-3-phenylpropanoic acid | CHEMBL386339
Type:
Small organic molecule
Emp. Form.:
C19H30N2O4SSi
Mol. Mass.:
410.603
SMILES:
C[Si](C)(C)CCC(=O)NC(CCS)C(=O)N[C@H](Cc1ccccc1)C(O)=O
Structure:
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