Reaction Details Report a problem with these data
Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50191991
Substrate
n/a
Meas. Tech.
ChEMBL_392530 (CHEMBL864291)
Ki
150±n/a nM
Citation
 Sun, Q; Law, A; Crowder, MW; Geysen, HM Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis. Bioorg Med Chem Lett 16:5169-75 (2006) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50191991
Synonyms:
(2R)-2-(4-mercapto-2-(7-nitro-1H-indole-2-carboxamido)butanamido)-3-phenylpropanoic acid | CHEMBL385075
Type:
Small organic molecule
Emp. Form.:
C22H22N4O6S
Mol. Mass.:
470.498
SMILES:
OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1
Structure:
Search PDB for entries with ligand similarity: