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Target
Muscleblind-like protein 1
Ligand
BDBM50405591
Substrate
n/a
Meas. Tech.
ChEMBL_2265571
Kd
4.0±n/a nM
Citation
 Ahamad, S; Bhat, SA The Emerging Landscape of Small-Molecule Therapeutics for the Treatment of Huntington's Disease. J Med Chem 65:15993-16032 (2022) [PubMed] 
Target
Name:
Muscleblind-like protein 1
Synonyms:
EXP | KIAA0428 | MBNL | MBNL1 | Muscleblind-like protein 1 | Triplet-expansion RNA-binding protein
Type:
PROTEIN
Mol. Mass.:
41833.94
Organism:
Homo sapiens
Description:
ChEMBL_103750
Residue:
388
Sequence:
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM
  
Inhibitor
Name:
BDBM50405591
Synonyms:
CHEMBL5286270
Type:
Small organic molecule
Emp. Form.:
C26H17BrN2O4
Mol. Mass.:
501.328
SMILES:
COc1ccc(cc1)C(=O)c1nc2c3cc(Br)ccc3oc(=O)c2c(-c2ccccc2)c1N
Structure:
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