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Target
Estrogen receptor alpha
Ligand
BDBM50610463
Substrate
n/a
Meas. Tech.
ChEMBL_2280986
IC50
400±n/a nM
Citation
 Tanwar, AK; Dhiman, N; Kumar, A; Jaitak, V Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. Eur J Med Chem 213:0 (2021) [PubMed] 
Target
Name:
Estrogen receptor alpha
Synonyms:
ESR | ESR1 | ESR1_BOVIN | NR3A1
Type:
PROTEIN
Mol. Mass.:
66503.29
Organism:
Bos taurus
Description:
EBI_17090
Residue:
596
Sequence:
MTMTLHTKASGMALLHQIQANELEPLNRPQLKIPLERPLGEVYMDSSKPAVYNYPEGAAYDFNAAAPASAPVYGQSGLPYGPGSEAAAFGANGLGAFPPLNSVSPSPLVLLHPPPQPLSPFLHPHGQQVPYYLENESSGYAVREAGPPAYYRPNSDNRRQGGRERLASTSDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRNEAVPSGDMRAANLWPSPIMIKHTKKNSPVLSLTADQMISALLEAEPPIIYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLALHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLRSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHFRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPANFGSAPPEDVNQSQLAPTGCTSSHSLQTYYITGEAENFPSTV
  
Inhibitor
Name:
BDBM50610463
Synonyms:
CHEBI:67889 | NYASOL
Type:
Small organic molecule
Emp. Form.:
C17H16O2
Mol. Mass.:
252.3077
SMILES:
Oc1ccc(\C=C/[C@@H](C=C)c2ccc(O)cc2)cc1 |r|
Structure:
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