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Target
C-type lectin domain family 4 member M
Ligand
BDBM50610685
Substrate
n/a
Meas. Tech.
ChEMBL_2281732
IC50
6100±n/a nM
Citation
 Sethi, A; Sanam, S; Alvala, M Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins. Eur J Med Chem 222:0 (2021) [PubMed] 
Target
Name:
C-type lectin domain family 4 member M
Synonyms:
CD209 antigen-like protein 1 | CD209L | CD209L1 | CD299 | CD_antigen=CD299 | CLC4M_HUMAN | CLEC4M | DC-SIGN-related protein | DC-SIGN2 | DC-SIGNR | Dendritic cell-specific ICAM-3-grabbing non-integrin 2 | L-SIGN | Liver/lymph node-specific ICAM-3-grabbing non-integrin
Type:
PROTEIN
Mol. Mass.:
45339.05
Organism:
Homo sapiens
Description:
ChEMBL_105433
Residue:
399
Sequence:
MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFMLLAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE
  
Inhibitor
Name:
BDBM50610685
Synonyms:
CHEMBL5276990
Type:
Small organic molecule
Emp. Form.:
C29H30N4O4S
Mol. Mass.:
530.638
SMILES:
CN(c1ccc(C)c(C)c1)S(=O)(=O)c1ccc2[nH]cc(C(=O)N3CCN(CC3)c3ccccc3)c(=O)c2c1
Structure:
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