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Target
D(4) dopamine receptor
Ligand
BDBM50198293
Substrate
n/a
Meas. Tech.
ChEMBL_453342 (CHEMBL902496)
Ki
167±n/a nM
Citation
 Grundt, P; Husband, SL; Luedtke, RR; Taylor, M; Newman, AH Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR. Bioorg Med Chem Lett 17:745-9 (2007) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50198293
Synonyms:
1-(benzofuran-3-ylmethyl)-4-(3,4-dichlorophenyl)piperidin-4-ol | CHEMBL246643
Type:
Small organic molecule
Emp. Form.:
C20H19Cl2NO2
Mol. Mass.:
376.276
SMILES:
OC1(CCN(Cc2coc3ccccc23)CC1)c1ccc(Cl)c(Cl)c1
Structure:
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