Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM50614057
Substrate
n/a
Meas. Tech.
ChEMBL_2295415
IC50
1.2±n/a nM
Citation
 Haque, R; Maity, D Small molecule-based fluorescent probes for the detection of ?-Synuclein aggregation states. Bioorg Med Chem Lett 86:0 (2023) [PubMed] 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50614057
Synonyms:
CHEMBL5286894
Type:
Small organic molecule
Emp. Form.:
C24H19NO4
Mol. Mass.:
385.412
SMILES:
COc1ccc(\C=C\C=C2/Oc3ccc(cc3C2=O)-c2ccc(OC)nc2)cc1
Structure:
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