Reaction Details Report a problem with these data
Target
23S rRNA methylase leader peptide
Ligand
BDBM25400
Substrate
n/a
Meas. Tech.
ChEMBL_2299084
IC50
63000±n/a nM
Citation
 Jeremia, L; Deprez, BE; Dey, D; Conn, GL; Wuest, WM Ribosome-targeting antibiotics and resistance  RSC Med Chem 14:624-643 (2023) [PubMed] 
Target
Name:
23S rRNA methylase leader peptide
Synonyms:
23S rRNA methylase leader peptide | Erythromycin resistance leader peptide | ermC
Type:
PROTEIN
Mol. Mass.:
3807.46
Organism:
Escherichia coli
Description:
ChEMBL_120978
Residue:
31
Sequence:
MLVFQMRYQMRYVDKTSTVLKQTKKSDYADK
  
Inhibitor
Name:
BDBM25400
Synonyms:
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol | CHEMBL68738 | CPA | N6-CyclopentylAdo | N6-cyclopentyladenosine (CPA) | cid_657378
Type:
Small organic molecule
Emp. Form.:
C15H21N5O4
Mol. Mass.:
335.3583
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12
Structure:
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