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Target
Carboxypeptidase B
Ligand
BDBM50201437
Substrate
n/a
Meas. Tech.
ChEMBL_453905 (CHEMBL885909)
IC50
1950±n/a nM
Citation
 Islam, I; Bryant, J; May, K; Mohan, R; Yuan, S; Kent, L; Morser, J; Zhao, L; Vergona, R; White, K; Adler, M; Whitlow, M; Buckman, BO 3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg Med Chem Lett 17:1349-54 (2007) [PubMed]  Article 
Target
Name:
Carboxypeptidase B
Synonyms:
CBPB1_PIG | CPB | CPB1
Type:
PROTEIN
Mol. Mass.:
47371.10
Organism:
Sus scrofa
Description:
ChEMBL_453905
Residue:
416
Sequence:
MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
  
Inhibitor
Name:
BDBM50201437
Synonyms:
2-(mercaptomethyl)-3-(piperidin-3-yl)propanoic acid | CHEMBL395661
Type:
Small organic molecule
Emp. Form.:
C9H17NO2S
Mol. Mass.:
203.302
SMILES:
OC(=O)C(CS)CC1CCCNC1 |w:7.6,3.5|
Structure:
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